Tasks

• Validation of internal standards for absolute quantification of nucleosides
• Native tiRNA analytics
• Nucleoside analytics using modern mass spectrometry techniques

Publications

• Ignatova, V. et al., The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programmes, accepted at Genes & Development.
• Hagelskamp, F.#, Borland, K.#, Ramos, J., Hendrick, A., Fu, D. and Kellner S. (2020) Broadly applicable oligonucleotide mass spectrometry for the analysis of RNA writers and erasers in vitro. Nucleic Acids Res. # shared 1st author PMID: 32083657
• Borland, K., Diesend, J., Ito-Kureha, T., Heissmeyer, V., Hammann, C., Buck, A.H., Michalakis, S. and Kellner, S. (2019) Production and Application of Stable Isotope-Labeled Internal Standards for RNA Modification Analysis. Genes (Basel), 10. PMID: 30621251