Research Topics

tRNAs are the most intensively modified RNAs with up to 16 modified residues (around 20% of the complete tRNA). Although the dynamic nature of tRNA modifications is crucial to cell survival, Loss or creation of certain RNA modifications are involved in cancer, neuronal diseases and mitochondrial diseases.

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The central dogma of molecular biology states that DNA is the storage of the genetic code, which is transcribed into messenger RNA (mRNA) and translated into proteins with the help of transfer RNA (tRNA) and ribosomal RNA (rRNA)

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